The Connection

Vitamin D deficiency is remarkably common in people with chronic pain conditions. While research is still evolving, low vitamin D levels have been associated with muscle pain, fibromyalgia, and other pain conditions. Correcting deficiency may help reduce pain in some people, though it's not a cure-all.1

Vitamin D and the Body2

  • Essential for bone health
  • Involved in muscle function
  • Affects immune system
  • May reduce inflammation
  • Role in nerve function

Pain Conditions Linked to Low Vitamin D

  • Fibromyalgia
  • Chronic widespread pain
  • Chronic low back pain
  • Rheumatoid arthritis
  • Osteoarthritis
  • Headaches and migraines
  • Muscle pain (myalgia)

Signs of Deficiency3

  • Muscle weakness
  • Bone pain
  • Fatigue
  • Depression
  • Frequent infections
  • Many have no symptoms

Who's at Risk

  • Limited sun exposure
  • Darker skin pigmentation
  • Older adults
  • Obesity
  • Chronic pain (less active)
  • Northern latitudes
  • Certain medications

Testing

  • Blood test: 25-hydroxyvitamin D
  • Optimal levels debated
  • Deficiency: below 20 ng/mL
  • Insufficiency: 20-30 ng/mL
  • Ask your doctor about testing

Sources of Vitamin D

Sun Exposure

  • 10-30 minutes midday sun
  • Depends on skin tone, latitude
  • Balance sun safety

Food Sources

  • Fatty fish (salmon, mackerel)
  • Fortified milk and cereals
  • Egg yolks
  • Fortified orange juice

Supplements

  • Vitamin D3 preferred
  • Typical doses: 1000-4000 IU daily
  • Higher doses need monitoring
  • Take with fat for absorption

Cautions

  • Too much can be harmful
  • Toxicity possible at very high doses
  • Get levels tested before high-dose supplements
  • Some medications interact

References

  1. Yong WC, Sanguankeo A, Upala S. Effect of vitamin D supplementation in chronic widespread pain: a systematic review and meta-analysis. Clin Rheumatol. 2017;36(12):2825-2833.
  2. Holick MF. Vitamin D deficiency. N Engl J Med. 2007;357(3):266-281.
  3. Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. Mayo Clin Proc. 2003;78(12):1463-1470.