Common Causes of Chronic Knee Pain

The knee is a complex joint that bears significant weight and stress. Chronic knee pain can result from various conditions, injuries, or degenerative changes. Understanding the cause helps guide treatment.1

Conditions Causing Knee Pain2

Degenerative

  • Osteoarthritis (most common)
  • Meniscus degeneration
  • Chondromalacia patella

Inflammatory

  • Rheumatoid arthritis
  • Gout
  • Pseudogout

Overuse/Mechanical

  • Patellofemoral pain syndrome
  • IT band syndrome
  • Patellar tendinopathy
  • Bursitis

Post-Injury

  • Meniscus tears
  • ACL/PCL injuries
  • Post-traumatic arthritis

Symptoms to Note

  • Location of pain
  • What makes it better/worse
  • Swelling
  • Locking or giving way
  • Stiffness pattern
  • Clicking or grinding

Treatment Approaches3

Conservative

  • Weight management (reduces load)
  • Exercise (quad strengthening essential)
  • Physical therapy
  • NSAIDs, topical treatments
  • Bracing
  • Activity modification

Interventional

  • Corticosteroid injections
  • Hyaluronic acid injections
  • PRP
  • Genicular nerve block/RFA

Surgical

  • Arthroscopy (limited indications)
  • Partial knee replacement
  • Total knee replacement

References

  1. Bunt CW, Jonas CE, Chang JG. Knee pain in adults and adolescents: the initial evaluation. Am Fam Physician. 2018;98(9):576-585.
  2. Deveza LA, Melo L, Yamato TP, et al. Knee osteoarthritis phenotypes and their relevance for outcomes. Osteoarthritis Cartilage. 2017;25(12):1926-1934.
  3. Skou ST, Roos EM. Good Life with osteoarthritis in Denmark (GLA:D). BMC Musculoskelet Disord. 2017;18(1):72.