What Is Endometriosis?

Endometriosis is a chronic condition where tissue similar to the uterine lining grows outside the uterus. It affects approximately 10% of women of reproductive age and is a leading cause of chronic pelvic pain. Diagnosis often takes years, and the condition can significantly impact quality of life.1

Symptoms2

Pain Symptoms

  • Painful periods (dysmenorrhea)
  • Chronic pelvic pain
  • Pain during or after sex
  • Painful bowel movements
  • Painful urination during periods
  • Lower back pain

Other Symptoms

  • Heavy periods
  • Infertility
  • Fatigue
  • Bloating ("endo belly")
  • Nausea
  • Bowel or bladder symptoms

Diagnosis Challenges

  • Average 7-10 years to diagnosis
  • Often dismissed as "normal" pain
  • Symptoms vary widely
  • Definitive diagnosis requires surgery
  • Imaging may not show lesions

Diagnostic Process3

  • Detailed history and exam
  • Pelvic ultrasound
  • MRI in some cases
  • Laparoscopy (gold standard)
  • Trial of treatment sometimes used

Treatment Options

Pain Management

  • NSAIDs
  • Heat therapy
  • Physical therapy
  • Nerve blocks in some cases

Hormonal Treatments

  • Birth control pills (continuous)
  • Progestins
  • GnRH agonists
  • GnRH antagonists (newer)
  • Aromatase inhibitors

Surgery

  • Laparoscopic excision (preferred)
  • Ablation of lesions
  • Hysterectomy (last resort)
  • Excision by specialist often best

Comprehensive Care

  • Multidisciplinary approach helpful
  • Pelvic floor physical therapy
  • Mental health support
  • Dietary modifications (some benefit)
  • Complementary therapies

Living with Endometriosis

  • Track symptoms and cycles
  • Find a knowledgeable provider
  • Advocate for yourself
  • Connect with support groups
  • Manage stress
  • Communicate with partners

References

  1. Zondervan KT, Becker CM, Missmer SA. Endometriosis. N Engl J Med. 2020;382(13):1244-1256.
  2. Agarwal SK, Chapron C, Giudice LC, et al. Clinical diagnosis of endometriosis: a call to action. Am J Obstet Gynecol. 2019;220(4):354.e1-354.e12.
  3. Giudice LC. Clinical practice: endometriosis. N Engl J Med. 2010;362(25):2389-2398.